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IGF-BP3 Recombinant Protein (0.005 mg)

IGF-BP3 Recombinant Protein (0.005 mg)

IGF-BP3 is a 30 kDa cysteine-rich secreted protein. It is the major IGF binding protein present in the plasma of human and animals and it is also found in alpha-granules of platelets. In addition to its ability to modulate the activity of IGF-I and IGF-II, IGF-BP3 exerts inhibitory effects on follicle stimulating hormone (FSH) activity. Decreased plasma levels of IGF-BP3 often results in dwarfism, whereas elevated levels of IGF-BP3 may lead to acromegaly. The expression of IGF-BP3 in fibroblasts is stimulated by mitogenic growth factors such as Bombesin, Vasopressin, PDGF, and EGF. Recombinant human IGF-BP3 is a 28.8 kDa protein consisting of 264 amino acid residues.

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SPECIFICATIONS

Size

0.005 mg

Presku

OPPB00059

Alternative Names

Insulin-like Growth Factor-Binding Protein 3; Growth-hormone-dependant binding protein

SUPPLIER INFO

Aviva Systems Biology Incorporated

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