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IDH2 Antibody (OAPB01130)

IDH2 Antibody (OAPB01130)

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Two NADP(+)-dependent isocitrate dehydrogenases have been found as homodimer: IDH1 is predominantly cytosolic and peroxisomal and IDH2 is mitochondrial. Both IDH1 and IDH2 play significant roles in the tricarboxylic acid cycle (TCA), and defects in IDH1 as well as IDH2 have been implicated in the development of glioma as well as other malignancies.

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SPECIFICATIONS

Size

0.1 mg

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Presku

OAPB01130

Target

Mitochondrial NADP-isocitrate dehydrogenase

Alternative Names

IDH2; Mitochondrial NADP-isocitrate dehydrogenase; IDH; IDP; IDHM; IDPM; ICD-M; mNADP-IDH

SUPPLIER INFO

Aviva Systems Biology Incorporated

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