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ID4 (inhibitor of DNA binding 4, dominant negative helix-loop-helix protein) Blocking Peptide (100ug)

ID4 (inhibitor of DNA binding 4, dominant negative helix-loop-helix protein) Blocking Peptide (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-ID4 antibody (Catalogue #: ARP38058_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP38058
Size: 100 ug
Weight: 17kDa
Gene: 3400
Format: Lyophilized powder
Target: Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins (Pagliuca et al., 1995).[supplied by OMIM].
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