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ICSBP Antibody

ICSBP Antibody

Cat no: 252105

Supplier: ABBIOTEC
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Interferon regulatory factor 8 (ICSBP) specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). ICSBP plays a negative regulatory role in cells of the immune system. ICSBP is ubiquitinated by TRIM21 in macrophages, a process that is strongly increased upon interferon gamma stimulation. This leads to the enhanced transcriptional activity of target cytokine genes.
Catalogue number: 252105
Reactivities: Human
Applications: Western Blot
Size: 0.1 mg
Accession: Q02556
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ICSBP.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Interferon regulatory factor 8; IRF-8; Interferon consensus sequence-binding protein; ICSBP; IRF8; ICSBP1
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