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ICSBP Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252105

ICSBP Antibody

Interferon regulatory factor 8 (ICSBP) specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). ICSBP plays a negative regulatory role in cells of the immune system. ICSBP is ubiquitinated by TRIM21 in macrophages, a process that is strongly increased upon interferon gamma stimulation. This leads to the enhanced transcriptional activity of target cytokine genes.

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SPECIFICATIONS

Catalog Number

252105

Size

0.1 mg

Applications

WB

Reactivities

Hum

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ICSBP.

Isotype

Rabbit Ig

Accession

Q02556

Additional Info

Interferon regulatory factor 8; IRF-8; Interferon consensus sequence-binding protein; ICSBP; IRF8; ICSBP1

SUPPLIER INFO

ABBIOTEC

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