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IAPP (islet amyloid polypeptide) Blocking Peptide (the N terminal of IAPP)(100ug)

IAPP (islet amyloid polypeptide) Blocking Peptide (the N terminal of IAPP)(100ug)

This is a synthetic peptide designed for use in combination with anti-IAPP Antibody(ARP41728_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100ug

Reactivities

Hum

Format

Lyophilized powder

Presku

AAP41728

Target

Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.

Weight

4kDa

Gene Id

3375

Alternative Names

AMYLIN; DAP; IAP

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