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HVCN1 Antibody (OAPB01154)

HVCN1 Antibody (OAPB01154)

HVCN1 (hydrogen voltage-gated channel 1), a voltage gated proton channel protein that is highly expressed in immune tissues, mediates the proton conductances required by phagocytic leukocytes for the oxidative burst that underlies microbial killing. HVCN1 moderates the voltage-dependent proton permeability of excitable membranes by allowing the flow of protons in accordance to their electrochemical gradient. HVCN1 is sensitive to zinc ions, and can be inhibited by them. HVCN1 may represent a new therapeutic target for B cell malignancies on continued signaling via the B cell antigen receptor.

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SPECIFICATIONS

Size

0.1 mg

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Presku

OAPB01154

Target

Hydrogen voltage-gated channel 1

Alternative Names

HVCN1; Hydrogen voltage-gated channel 1; HV1; VSOP; Voltage sensor domain-only protein

SUPPLIER INFO

Aviva Systems Biology Incorporated

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