Human TGF-beta-inducible early response gene-1 (TIEG1) ELISA Kit

Tachibana et al. characterized the expression and function in exocrine pancreatic epithelial cells of the TGF-beta-inducible early gene (TIEG), a Kruppel-like zinc finger transcription factor-encoding gene previously isolated from mesodermally derived osteoblastic cells by Subramaniam et al. Tachibana et al. demonstrated that the gene is expressed in both acinar and ductular epithelial cell populations from the exocrine pancreas. In addition, they showed that the expression of TIEG is regulated by TGF-beta-1 (TGFB1) as an early response gene in pancreatic epithelial cell lines. Overexpression of TIEG in a TGF-beta-sensitive epithelial cell line was sufficient to induce apoptosis. Thus, Tachibana et al. concluded that TIEG plays a role in linking TGF-beta-mediated signaling cascades to the regulation of pancreatic epithelial cell growth.

Prices direct from Abbkine Scientific Co.Ltd.

Quick response times

Exclusive Absave savings/discounts

SPECIFICATIONS

Catalog Number

KTE61907

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

7071

Accession

Q13118

Additional Info

Human TGF-beta-inducible early response gene-1 (TIEG1) ELISA Kit has high sensitivity and excellent specificity for detection of Human KLF10. No significant cross-reactivity or interference between Human KLF10 and analogues was observed.