Human Low-density lipoprotein-receptor-related protein (LRP-6) ELISA Kit

The LRP6 is a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.

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SPECIFICATIONS

Catalog Number

KTE61781

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

4040

Accession

O75581

Additional Info

Human Low-density lipoprotein-receptor-related protein (LRP-6) ELISA Kit has high sensitivity and excellent specificity for detection of Human LRP6. No significant cross-reactivity or interference between Human LRP6 and analogues was observed.