Human Lipolysaccharide binding protein (LBP) ELISA Kit

LPS-binding protein (LBP) is serum factor known to regulate the endotoxin-induced cellular immune response. Sepsis is a morbid condition induced by a toxin, the introduction or accumulation of which is most commonly caused by infection or trauma. Sepsis-inducing toxins have been found associated with pathogenic bacteria, viruses, plants and venoms.\nAmong the well described bacterial toxins are the endotoxins or lipopolysaccharides (LPS) of the gram-negative bacteria. Upon introduction of LPS into the blood it binds to lipopolysaccharide binding protein (LBP). LBP recognizes the lipid A region of LPS and forms high affinity complexes with both rough and smooth form LPS. During the acute phase, LBP is synthesized by hepatocytes, and reaches very high concentrations in serum.

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SPECIFICATIONS

Catalog Number

KTE61850

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

3929

Accession

P18428

Additional Info

Human Lipolysaccharide binding protein (LBP) ELISA Kit has high sensitivity and excellent specificity for detection of Human LBP. No significant cross-reactivity or interference between Human LBP and analogues was observed.