Human Leucyl-cystinyl aminopeptidase (LNPEP) ELISA Kit

LNPEP encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms.\nThe deduced 944-amino acid polypeptide contains the HEXXH consensus sequence of zinc metallopeptidases as well as an N-terminal hydrophobic region that resembles a transmembrane domain.

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SPECIFICATIONS

Catalog Number

KTE61802

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

4012

Accession

Q9UIQ6

Additional Info

Human Leucyl-cystinyl aminopeptidase (LNPEP) ELISA Kit has high sensitivity and excellent specificity for detection of Human LNPEP. No significant cross-reactivity or interference between Human LNPEP and analogues was observed.