Human LETM1 and EF-hand domain-containing protein 1, mitochondrial (LETM1) ELISA Kit

LETMD1 is involved in tumorigenesis and may function as a negative regulator of the TP53/p53. It is found in kidney, liver, skeletal muscle, heart and brain and is over-expressed in various tumors including leukemia, lymphoma, and carcinomas of the breast, kidney, ovary, stomach, colon and uterine cervix. There are six isoforms.HCCR-2 that was overexpressed in various human tumors including leukemia, lymphoma, and carcinomas of the breast, kidney, ovary, stomach, colon, and uterine cervix. Ectopic expression of HCCR-2 resulted in direct tumorigenic conversions of NIH/3T3 and Rat1 fibroblasts. HCCR-2 probably represents a new oncogene that is related to tumorigenesis, functioning as a negative regulator of the p53 tumor suppressor.

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SPECIFICATIONS

Catalog Number

KTE61828

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

3954

Accession

O95202

Additional Info

Human LETM1 and EF-hand domain-containing protein 1, mitochondrial (LETM1) ELISA Kit has high sensitivity and excellent specificity for detection of Human LETM1. No significant cross-reactivity or interference between Human LETM1 and analogues was observed.