Human Kinesin-like protein KIF1A (KIF1A) ELISA Kit

KIF1A is a member of the kinesin family. This protein is highly similar to mouse heavy chain kinesin member 1A protein which is an anterograde motor protein that transports membranous organelles along axonal microtubules. It is thought that this protein may play a critical role in the development of axonal neuropathies resulting from impaired axonal transport. There are multiple polyadenylation sites found in this gene.\nThis switch-like transition for movement could be shifted to lower PtdIns(4,5)P2 concentrations by the addition of cholesterol/sphingomyelin or GM1 ganglioside/cholera toxin, conditions that produced raft-like behavior of Unc104 bound to lipid bilayers. The authors concluded that clustering of Unc104 in PtdIns(4,5)P2-containing rafts provides a trigger for membrane transport.

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SPECIFICATIONS

Catalog Number

KTE61918

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

547

Accession

Q12756

Additional Info

Human Kinesin-like protein KIF1A (KIF1A) ELISA Kit has high sensitivity and excellent specificity for detection of Human KIF1A. No significant cross-reactivity or interference between Human KIF1A and analogues was observed.