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Human Factor XII ELISA Kit 1 Kit (96 Wells)

Cat no: IHFXIIKT-TOT-1 Kit (96 Wells)

Human Factor XII ELISA Kit 1 Kit (96 Wells)

The assay measures total human Factor XII in the 0.1-100 ng/mL range. Samples giving human Factor XII levels above 100ng/mL should be diluted in blocking buffer before use. A 1:1,000 to 1:5,000 dilution for plasma is suggested for best results. The concentration of Factor XII in normal human plasma has been found to be 29 пїЅg/mL, with variation among individuals from 15 to 47 пїЅg/mL. Another series of studies found values in the 35-40 пїЅg/mL range.
style=text-align: justify;Factor XII (aka Hageman Factor) is a single-chain, 615 amino acid glycoprotein zymogen. Factor XII is activated by kallikrein. Factor XIIa converts prekallikrein to kallikrein during the intrinsic pathway of the coagulation cascade. Although Factor XII is not thought to play an essential role in normal hemostasis, lack of Factor XII in a mouse model resulted in a пїЅпїЅsevere defectпїЅпїЅ in thrombus formation.
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SPECIFICATIONS

Catalog Number

IHFXIIKT-TOT-1 Kit (96 Wells)

Size

EA

Certificate Of Analysis

http://www.innov-research.com/contact-factors/487-human-factor-xii-elisa-kit.html

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