Human Dual Specificity Plaosplaatase (DUSP1) ELISA Kit

Dual specificity protein phosphatase 1 is an enzymeinduced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes.

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SPECIFICATIONS

Catalog Number

KTE61969

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

1843

Accession

P28562

Additional Info

Human Dual Specificity Plaosplaatase (DUSP1) ELISA Kit has high sensitivity and excellent specificity for detection of Human DUSP1. No significant cross-reactivity or interference between Human DUSP1 and analogues was observed.