Human Disks large homolog 3 (DLG3) ELISA Kit

DLG3 is a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked mental retardation. Alternatively spliced transcript variants have been described.\nThe predicted 817-amino acid protein contains the 3 DHR segments, central SH3 motif, and C-terminal guanylate kinase domain characteristic of MAGUK proteins. NEDLG shares 75% and 60% protein sequence identity with DLG1 and Drosophila dlg, respectively. NEDLG is highly expressed in neuronal and endocrine tissues.

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SPECIFICATIONS

Catalog Number

KTE62028

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

1741

Accession

Q92796

Additional Info

Human Disks large homolog 3 (DLG3) ELISA Kit has high sensitivity and excellent specificity for detection of Human DLG3. No significant cross-reactivity or interference between Human DLG3 and analogues was observed.