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HSPB8 (heat shock 22kDa protein 8) Blocking Peptide (the middle region of HSPB8)(100ug)

HSPB8 (heat shock 22kDa protein 8) Blocking Peptide (the middle region of HSPB8)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-HSPB8 Antibody(ARP55036_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP55036
Size: 100ug
Weight: 21kDa
Gene: 26353
Format: Lyophilized powder
Target: HSPB8 belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of HSPB8 protein is induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, HSPB8 appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in the encoding HSPB8 gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
Alternative names: CMT2L; DHMN2; E2IG1; H11; HMN2; HMN2A; HSP22
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