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HSD11B1 (hydroxysteroid (11-beta) dehydrogenase 1) Blocking Peptide (the N terminal of protein) (100ug)

HSD11B1 (hydroxysteroid (11-beta) dehydrogenase 1) Blocking Peptide (the N terminal of protein) (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-HSD11B1 antibody (Catalogue #: ARP45714_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP45714
Size: 100 ug
Weight: 32kDa
Gene: 3290
Format: Lyophilized powder
Target: HSD11B1 is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, HSD11B1 can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children.The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene.
Alternative names: 11-DH; 11-beta-HSD1; HDL; HSD11; HSD11B; HSD11L; MGC13539
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