Reactivities: | Human, Mouse |
Presku: | AAP40516 |
Size: | 100ug |
Weight: | 34kDa |
Gene: | 15381 |
Format: | Lyophilized powder |
Target: | Hnrnpc binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. Hnrnpc may play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Hnrnpc interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules. |
Alternative names: | AL022939; D14Wsu171e; Hnrpc; Hnrpc1; Hnrpc2; hnRNPC1; hnRNPC2; hnrnp-C |