
Supplier:
Aviva Systems Biology IncorporatedHmgn3 Antibody - middle region (ARP61954_P050)
Prices direct from Aviva Systems Biology Incorporated
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SPECIFICATIONS
Size
50ug
Applications
WB
Hosts
Rabbit
Reactivities
Hum, Mouse
Format
Lyophilized powder
Presku
ARP61954_P050
Target
Hmgn3 binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. It affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion, regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors and regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. It may play a role in ocular development and astrocyte function.
Weight
11kDa
Gene Id
94353
Alternative Names
1110002A15Rik; 6330514M13Rik; BB071015; TRIP7
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