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HMGCL (Human) cDNA (1ug)

HMGCL (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human HMGCL is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-HMGCL polyclonal antibody.
Presku: ANA10424
Size: 1ug
Gene: 3155
Target: The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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