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HMGB2 (Human) cDNA (1ug)

HMGB2 (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human HMGB2 is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-HMGB2 polyclonal antibody.
Presku: ANA10929
Size: 1ug
Gene: 3148
Target: This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
Alternative names: HMG2
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