HLA-E (major histocompatibility complex, class I, E ) Blocking Peptide (the C terminal of HLA-E)(100ug)

This is a synthetic peptide designed for use in combination with anti-HLA-E Antibody (ARP62847_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100ug

Reactivities

Hum

Format

Lyophilized powder

Presku

AAP62847

Target

HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.

Weight

38kDa

Gene Id

The peptide is characterized by mass spectroscopy

Alternative Names

DKFZp686P19218; EA1.2; EA2.1; HLA-6.2; MHC; QA1