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HLA-DMA (major histocompatibility complex, class II, DM alpha ) Blocking Peptide (the N terminal of HLA-DMA)(100ug)

HLA-DMA (major histocompatibility complex, class II, DM alpha ) Blocking Peptide (the N terminal of HLA-DMA)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-HLA-DMA Antibody (ARP61256_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP61256
Size: 100ug
Weight: 29kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail.
Alternative names: D6S222E; DMA; HLADM; RING6
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