Home  >  Products  >  HLA-C (major histocompatibility complex, class I, C ) Blocking Peptide (the C terminal of HLA-C)(100ug)
HLA-C (major histocompatibility complex, class I, C ) Blocking Peptide (the C terminal of HLA-C)(100ug)

HLA-C (major histocompatibility complex, class I, C ) Blocking Peptide (the C terminal of HLA-C)(100ug)

Supplier: Aviva Systems Biology Incorporated
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
This is a synthetic peptide designed for use in combination with anti-HLA-C Antibody (ARP63059_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP63059
Size: 100ug
Weight: 38kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described.
Alternative names: D6S204; FLJ27082; HLA-Cw; HLA-Cw12; HLA-JY3; HLC-C; PSORS1
See Full Product Listings >