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HIST2H2BF (Human) cDNA (1ug)

HIST2H2BF (Human) cDNA (1ug)

The ORF of human HIST2H2BF is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-HIST2H2BF polyclonal antibody.

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SPECIFICATIONS

Size

1ug

Presku

ANA11492

Target

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene Id

440689

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