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HIST2H2BF (Human) cDNA (1ug)

HIST2H2BF (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human HIST2H2BF is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-HIST2H2BF polyclonal antibody.
Presku: ANA11492
Size: 1ug
Gene: 440689
Target: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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