Presku: | AAP30572 |
Size: | 100 ug |
Weight: | 93kDa |
Gene: | 3091 |
Format: | Lyophilized powder |
Target: | Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). HIF1A is the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. |
Alternative names: | HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8 |