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HIF-1 alpha Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251256

HIF-1 alpha Antibody

Hypo, Xenopus/Amphibian,ia-inducible factor 1-alpha (HIF-1 alpha) functions as a master transcriptional regulator of the adaptive response to hypo, Xenopus/Amphibian,ia. Under hypo, Xenopus/Amphibian,ic conditions, HIF-1 alpha activates the transcription of over 40 genes, including, erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, and other genes whose protein products increase o, Xenopus/Amphibian,ygen delivery or facilitate metabolic adaptation to hypo, Xenopus/Amphibian,ia. HIF-1 alpha plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. HIF-1 alpha binds to core DNA sequence 5'-[AG]CGTG-3' within the hypo, Xenopus/Amphibian,ia response element (HRE) of target gene promoters.

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SPECIFICATIONS

Catalog Number

251256

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Bov, Can, Ch/Bird, Prc, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human HIF-1 alpha.

Isotype

Rabbit Ig

Accession

Q16665

Additional Info

Hypo, Xenopus/Amphibian,ia-inducible factor 1 alpha; HIF-1 alpha; HIF1 alpha; ARNT-interacting protein; Member of PAS protein 1; Basic-heli, Xenopus/Amphibian,-loop-heli, Xenopus/Amphibian,-PAS protein MOP1; HIF1A; MOP1

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