Supplier:
Aviva Systems Biology IncorporatedHEXA antibody - C-terminal region (ARP61100_P050)
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SPECIFICATIONS
Size
50ug
Applications
IHC, WB
Hosts
Rabbit
Reactivities
Hum
Format
Lyophilized powder
Presku
ARP61100_P050
Target
This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).
Weight
48kDa
Gene Id
3073
Alternative Names
MGC99608; TSD
SUPPLIER INFO
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