Reactivities: | Human, Mouse |
Presku: | AAP32897 |
Size: | 100ug |
Weight: | 24kDa |
Gene: | 55927 |
Format: | Lyophilized powder |
Target: | Hes6 does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Hes6 also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. It promotes cell differentiation. |
Alternative names: | AI326893; bHLHb41 |