Supplier:
Aviva Systems Biology IncorporatedHERV-FRD antibody - N-terminal region (ARP56008_P050)
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SPECIFICATIONS
Size
50ug
Applications
WB
Hosts
Rabbit
Reactivities
Hum
Format
Lyophilized powder
Presku
ARP56008_P050
Target
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has retained its original fusogenic properties. HERV-FRD can make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity.Human endogenous retroviruses (HERVs) make up approximately 8% of the human genome. Although most HERVs are nonfunctional, the HERV-W (ERVWE1; MIM 604659) and HERV-FRD envelope (env) proteins can induce cell-cell fusion when expressed in cells possessing appropriate receptors (Blaise et al., 2003 [PubMed 14557543]).[supplied by OMIM].
Weight
55kDa
Gene Id
405754
Alternative Names
FLJ41944; FLJ90611; GLLL6191; MGC87585; UNQ6191; envFRD; ERVFRDE1; HERV-FRD; HERV-W/FRD
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