Reactivities: | Human |
Presku: | AAP43237 |
Size: | 100ug |
Weight: | 115kDa |
Gene: | 55008 |
Format: | Lyophilized powder |
Target: | HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]). |
Alternative names: | FLJ20637 |