Supplier:
Aviva Systems Biology IncorporatedHERC5 antibody - N-terminal region (ARP43212_P050)
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SPECIFICATIONS
Size
50ug
Applications
WB
Hosts
Rabbit
Reactivities
Hum, Bov
Format
Lyophilized powder
Presku
ARP43212_P050
Target
HERC5 is a probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
Weight
117kDa
Gene Id
51191
Alternative Names
CEB1; CEBP1
SUPPLIER INFO
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