Reactivities: | Human, Mouse |
Presku: | AAP38730 |
Size: | 100ug |
Weight: | 126kDa |
Gene: | 15185 |
Format: | Lyophilized powder |
Target: | Hdac6 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Hdac6 plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. |
Alternative names: | Hd6; Hdac5; Sfc6; mHDA2 |