HDAC4 Protein Lysate (GST tagged) (Expressed in bacteria) (200ug)

Supplier: Aviva Systems Biology Incorporated

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Partial length HDAC4 is expressed in E. coli.

Presku:	APL10198
Size:	200ug
Weight:	48
Gene:	9759
Target:	Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Alternative names:	HD4; AHO3; BDMR; HDACA; HA6116; HDAC-A; KIAA0288; HDAC-4