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HDAC3 (7G6C) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252811

HDAC3 (7G6C) Antibody

HDAC3 (Histone deacetylase 3) is a histone deacetylase protein. Histones play a critical role in transcriptional regulation, cell cycle progression and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

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SPECIFICATIONS

Catalog Number

252811

Size

0.1 ml

Applications

IF

Reactivities

Hum

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of human HDAC3 (aa224-428) e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG2a

Accession

O15379

Clonality

7G6C5

Additional Info

Histone deacetylase 3; HD3; RPD3-2; SMAP45; HDAC3

SUPPLIER INFO

ABBIOTEC

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