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HCCR-1 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 250682

HCCR-1 Antibody

Human cervical cancer oncogene (HCCR-1) is a human oncoprotein, and has shown strong tumorigenic features. Its role in tumorogenesis is from a negative regulation of the p53 tumor suppressor gene. HCCR-1 is located in mitochondrial outer membrane, where its function is to retard intrinsic apoptosis e, Xenopus/Amphibian,perimentally-induced by UVC and staurosporine. Uncontrolled e, Xenopus/Amphibian,pression of HCCR-1 causes mitochondrial dysfunction, resulting in the progression of tumor formation. HCCR-1 has also been shown to be a regulatory factor that stimulates morphogenesis of epithelia or mesenchyme during neoplastic transformation.

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SPECIFICATIONS

Catalog Number

250682

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Bov, Can, Ch/Bird, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human HCCR-1.

Isotype

Rabbit Ig

Accession

Q8WY22

Additional Info

HCCR-1; BRI3-binding protein; I3-binding protein; Cervical cancer 1 proto-oncogene-binding protein KG19; BRI3BP

SUPPLIER INFO

ABBIOTEC

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