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HAVCR2 Protein Lysate (GST tagged) (Expressed in bacteria) (200ug)

HAVCR2 Protein Lysate (GST tagged) (Expressed in bacteria) (200ug)


Supplier: Aviva Systems Biology Incorporated
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Partial length HAVCR2 is expressed in E. coli.
Presku: APL10721
Size: 200ug
Weight: 41
Gene: 84868
Target: CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.
Alternative names: TIM3; KIM-3; TIMD3; Tim-3; FLJ14428; TIMD-3; HAVcr-2