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Hand2 (heart and neural crest derivatives expressed transcript 2) Blocking Peptide (the C terminal of Hand2)(100ug)

Hand2 (heart and neural crest derivatives expressed transcript 2) Blocking Peptide (the C terminal of Hand2)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Hand2 Antibody (ARP30571_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Mouse
Presku: AAP30571
Size: 100ug
Weight: 24kDa
Gene: 15111
Format: Lyophilized powder
Target: Hand2 is essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. It is required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. It plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Hand2 is involved in the development of branchial arches, which give rise to unique structures in the head and neck.
Alternative names: AI225906; AI661148; Ehand2; Hed; Th2; Thing2; bHLHa26; dHAND
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