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Hamster Anti- Mouse TCRgd- FITC(0.5 mg)

Hamster Anti- Mouse TCRgd- FITC(0.5 mg)

The TCR?delta heterodimer of the CD3/T-cell receptor complex is clonotypic and consists of Ig-like variable and constant domains.1 It is expressed during thymopoiesis and on the small subpopulation of ?delta TCRexpressing T lymphocytes in the periphery. The majority of T cells present in some epithelial tissues are ?delta+ and have limited receptor diversity.1, 2 The TCR?delta heterodimer recognizes peptide antigen bound to MHC antigens, and subsequent signal transduction mediated by the invariant chains leads to T cell activation.3 The monoclonal antibody UC7-13D5 is specific for the ?delta heterodimer and plate-bound UC7-13D5 activates ?delta TCR-bearing cells.4-7 This antibody does not react with alpha beta TCR-expressing T cells.

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SPECIFICATIONS

Size

0.5 mg

Applications

FC

Hosts

Ham

Clone

UC7- 13D5

Format

Fluorescein (FITC) Conjugate

Presku

OASB01704

Isotype

IgG

SUPPLIER INFO

Aviva Systems Biology Incorporated

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