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Hamster Anti- Mouse CD81- UNLB(0.5 mg)

Hamster Anti- Mouse CD81- UNLB(0.5 mg)

CD81/TAPA-1 is an integral membrane protein expressed on a variety of cell types, and has a high degree of sequence homology between human and mouse.1 CD81 is expressed on thymic stromal cells where it plays an important role in the transition of gammadelta+ T cells to more mature T cells with alpha beta T cell receptors.2 Immunohistochemical staining has revealed that its expression is localized to the subcapsular region of the thymus and, specifically, on cells that have distinct clustering patterns. It has been speculated that the ligand for CD81 is the pre-T cell receptor, which is composed of a TCR beta chain and glycoprotein pTalpha.2 The monoclonal antibody 2F7 can block thymocyte interaction with CD81 in vitro.2

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SPECIFICATIONS

Size

0.5 mg

Applications

FC

Hosts

Ham

Clone

2F7

Format

Purified (UNLB) Antibody

Presku

OASB01743

Isotype

IgG

SUPPLIER INFO

Aviva Systems Biology Incorporated

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