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H2AFZ (H2A histone family, member Z ) Blocking Peptide (the N terminal of H2AFZ)(100ug)

H2AFZ (H2A histone family, member Z ) Blocking Peptide (the N terminal of H2AFZ)(100ug)


Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-H2AFZ Antibody (ARP61354_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP61354
Size: 100ug
Weight: 14kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.
Alternative names: H2A.z; H2A/z; H2AZ; MGC117173