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GRM6 (glutamate receptor, metabotropic 6) Blocking Peptide (the middle region of protein) (100ug)

GRM6 (glutamate receptor, metabotropic 6) Blocking Peptide (the middle region of protein) (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-GRM6 antibody (Catalogue #: ARP31907_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP31907
Size: 100 ug
Weight: 95kDa
Gene: 2916
Format: Lyophilized powder
Target: GRM6 is the receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity.L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Alternative names: CSNB1B; DKFZp686H1993; GPRC1F; MGLUR6; mGlu6
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