Reactivities: | Human, Rat |
Presku: | AAP35009 |
Size: | 100ug |
Weight: | 97kDa |
Gene: | 29628 |
Format: | Lyophilized powder |
Target: | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. |
Alternative names: | GLUR3; GluA3|GluR-3|GluR-C|GluR-K3 |