Reactivities: | Human, Mouse |
Presku: | AAP42380 |
Size: | 100ug |
Weight: | 21kDa |
Gene: | 23892 |
Format: | Lyophilized powder |
Target: | Grem1 is a cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as BMP a antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. It down-regulates the BMP4 signaling in a dose-dependent manner and acts as inhibitor of monocyte chemotaxis. |
Alternative names: | Cktsf1b1; Drm; ld |