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Products GRAP Protein Lysate (GST tagged) (Expressed in bacteria) (200ug)
| Presku: | APL10831 |
| Size: | 200ug |
| Weight: | 40 |
| Gene: | 10750 |
| Target: | This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. |
| Alternative names: | MGC64880 |
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