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Granzyme B Recombinant Protein (0.002 mg)

Granzyme B Recombinant Protein (0.002 mg)

Granzyme B is a cysteine protease found in the cytoplasmic granules of cytolytic T lymphocytes (CTL) and natural killer (NK) cells. Granzyme B is required for the induction of target cell lysis, which occurs as part of cell mediated immune responses, and can activate apoptosis in target cells by both caspase dependent and caspase independent mechanisms. Proteolytic cleavage of substrates by Granzyme B takes place primarily after aspartic acid residues. Recombinant murine Granzyme B is a glycosylated 227 amino acid protein, comprising the mature active portion of the murine Granzyme B precursor. The apparent molecular weight is 28.9 kDa by mass spectrometry.

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SPECIFICATIONS

Size

0.002 mg

Presku

OPPB00032

Alternative Names

Granzyme B

SUPPLIER INFO

Aviva Systems Biology Incorporated

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