Reactivities: | Human |
Presku: | AAP65672 |
Size: | 100ug |
Weight: | 44kDa |
Gene: | 53831 |
Format: | Lyophilized powder |
Target: | GPR84 is a receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. GPR84 is not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. GPR84 may have important roles in processes from fatty acid metabolism to regulation of the immune system. |
Alternative names: | EX33; GPCR4 |