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GPR68 (G protein-coupled receptor 68 ) Blocking Peptide (the middle region of GPR68)(100ug)

GPR68 (G protein-coupled receptor 68 ) Blocking Peptide (the middle region of GPR68)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-GPR68 Antibody (ARP64436_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP64436
Size: 100ug
Weight: 41kDa
Gene: 8111
Format: Lyophilized powder
Target: Proton-sensing receptor is involved in pH homeostasis. GPR68 may represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. GPR68 mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca2+ mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer.
Alternative names: MGC111379; MGC156983; OGR1
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