Reactivities: | Human |
Presku: | AAP62244 |
Size: | 100ug |
Weight: | 42kDa |
Gene: | The peptide is characterized by mass spectroscopy |
Format: | Lyophilized powder |
Target: | This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. |
Alternative names: | CEPR; CMKRL2; DRY12; FEG-1; GPCR-Br; GPR30; LERGU; LERGU2; LyGPR; MGC99678 |