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gp120 Antibody (OAPB00696)

gp120 Antibody (OAPB00696)

Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.

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SPECIFICATIONS

Size

0.1 mg

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Virus

Presku

OAPB00696

Target

(NT) HIV-1 glycoprotein 120

Alternative Names

gp120 (NT); HIV-1 glycoprotein 120

SUPPLIER INFO

Aviva Systems Biology Incorporated

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